Target-selective degradation of proteins by porphyrins upon visible photo-irradiation.

نویسندگان

  • Shuho Tanimoto
  • Shuichi Matsumura
  • Kazunobu Toshima
چکیده

A porphyrin derivative effectively and selectively degraded the target transcription factor, human estrogen receptor-alpha (hER-alpha), upon visible light irradiation, in the absence of additives and under neutral conditions.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Response surface methodology for optimization of Phenol photo-catalytic degradation using Carbon-doped TiO2 nano-photocatalyst

In this research, Carbon-doped TiO2 nano-photocatalyst is synthesized via sol-gel technique and photo-catalytic degradation of phenol has been studied under ultraviolet and visible light irradiation in a fluidized bed reactor. Various techniques are used to characterize TiO2 nano-photocatalyst such as X-Ray Diffraction, Fourier transform infrared spectroscopy,  Energy Disp...

متن کامل

Response surface methodology for optimization of Phenol photo-catalytic degradation using Carbon-doped TiO2 nano-photocatalyst

In this research, Carbon-doped TiO2 nano-photocatalyst is synthesized via sol-gel technique and photo-catalytic degradation of phenol has been studied under ultraviolet and visible light irradiation in a fluidized bed reactor. Various techniques are used to characterize TiO2 nano-photocatalyst such as X-Ray Diffraction, Fourier transform infrared spectroscopy,  Energy Disp...

متن کامل

Molecular design, chemical synthesis, and biological evaluation of agents that selectively photo-degrade the transcription factor estrogen receptor-α.

2-Phenylquinoline (1) degraded proteins under photo-irradiation with long-wavelength UV light without additives and under neutral conditions. We designed and synthesized a 2-phenylquinoline-estrogen receptor-α (ER-α) agonist (hybrid 2) and a 2-phenylquinoline-ER-α antagonist (hybrid 3) containing estradiol and 4-hydroxytamoxifen moieties, respectively. These 2-phenylquinoline hybrids effectivel...

متن کامل

Target-selective photo-degradation of HIV-1 protease by a fullerene-sugar hybrid.

A designed fullerene-sugar hybrid effectively and selectively degraded the target protein, HIV-1 protease, which has high affinity for the fullerene moiety; degradation was achieved using long-wavelength UV or visible photo-irradiation, in the absence of any additives and under neutral conditions.

متن کامل

Biosynthesis of MgFe2O4 magnetic nanoparticles and its application in photo-degradation of malachite green dye and kinetic study

In this study, we have reported the green synthesis magnesium ferrite using tragacanth gel by the sol-gel method without using any organic chemicals. The sample was characterized by powder X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), vibrating sample magnetometer (VSM) and scanning electron microscopy (SEM). The X-ray powder diffraction (XRD) analysis revealed the fo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Chemical communications

دوره 31  شماره 

صفحات  -

تاریخ انتشار 2008